BTLA - B- and T-lymphocyte attenuator - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
BTLA »  B- and T-lymphocyte attenuator
 
Protein also known as:  CD antigen CD272.
Gene name:  BTLA
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 35 2
GENE REF ISO

Function

 show evidences
Overview 
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.  
1
  • CuratedUniProtKB
GO molecular function 
Receptor activitydefinition[GO:0004872] silver  
  • IEAOrtholog Compara
GO biological process 
Immune response-regulating cell surface receptor signaling pathwaydefinition[GO:0002768] silver  
  • IEAOrtholog Compara
Negative regulation of alpha-beta T cell proliferationdefinition[GO:0046642] silver  
  • IEAOrtholog Compara
Negative regulation of B cell proliferationdefinition[GO:0030889] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Costimulation by the CD28 family  REACT_19344  
 

Keywords

Biological process 
Adaptive immunity  definition   [KW-1064]
Immunity  definition   [KW-0391]
Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BTLA
GenomeRNAi: 151888
PRO: PR:Q7Z6A9