CNTRL - Centriolin - human protein (Function)
 
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Protein
Gene
References

 
CNTRL »  Centriolin
 
Protein also known as:  Centrosomal protein of 110 kDa (Cep110).
Gene name:  CNTRL
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission.  
3
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
GO biological process 
Cell divisiondefinition[GO:0051301]  
1
  • UniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
Anchoring of the basal body to the plasma membrane  R-HSA-5620912  
Loss of Nlp from mitotic centrosomes  R-HSA-380259  
Loss of proteins required for interphase microtubule organization from the centrosome  R-HSA-380284  
Recruitment of mitotic centrosome proteins and complexes  R-HSA-380270  
Regulation of PLK1 Activity at G2/M Transition  R-HSA-2565942  
Signaling by FGFR1 fusion mutants  R-HSA-1839117  
Signaling by FGFR1 in disease  R-HSA-5655302  
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Cell division  definition   [KW-0132]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CNTRL
GenomeRNAi: 11064
PRO: PR:Q7Z7A1