CLNK - Cytokine-dependent hematopoietic cell linker - human protein (Function)
 
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Protein
Gene
References

 
CLNK »  Cytokine-dependent hematopoietic cell linker
 
Protein also known as:  Mast cell immunoreceptor signal transducer.
Gene name:  CLNK
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT (By similarity).  
1
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
SH3/SH2 adaptor activitydefinition[GO:0005070]  
1
  • UniProtKB
GO biological process 
Immune responsedefinition[GO:0006955]  
2
  • UniProtKB
  • RefGenome
Intracellular signal transductiondefinition[GO:0035556]  
1
  • UniProtKB
Positive regulation of signal transductiondefinition[GO:0009967]  
1
  • GOC
Transmembrane receptor protein tyrosine kinase signaling pathwaydefinition[GO:0007169]  
1
  • RefGenome
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 116449
PRO: PR:Q7Z7G1