DSG4 - Desmoglein-4 - human protein (Function)
 
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Protein
Gene
References

 
DSG4 »  Desmoglein-4
 
Protein also known as:  Cadherin family member 13.
Gene name:  DSG4
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAOrtholog Compara
GO biological process 
Anagendefinition[GO:0042640] silver  
  • IEAOrtholog Compara
BMP signaling pathwaydefinition[GO:0030509] silver  
  • IEAOrtholog Compara
Homophilic cell adhesiondefinition[GO:0007156] silver  
  • IEAInterPro 2 GO
Keratinocyte differentiationdefinition[GO:0030216] silver  
  • IEAOrtholog Compara
Single organismal cell-cell adhesiondefinition[GO:0016337] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DSG4
GenomeRNAi: 147409
PRO: PR:Q86SJ6