GLRX5 - Glutaredoxin-related protein 5, mitochondrial - human protein (Function)
 
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Protein
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GLRX5 »  Glutaredoxin-related protein 5, mitochondrial
 
Protein also known as:  Monothiol glutaredoxin-5.
Gene name:  GLRX5
Family name: Glutaredoxin » UPF0055
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.  
  • CuratedUniProtKB
GO molecular function 
2 iron, 2 sulfur cluster bindingdefinition[GO:0051537]  
  • IEAUniProtKB KW
Electron carrier activitydefinition[GO:0009055] silver  
  • IEAInterPro 2 GO
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein disulfide oxidoreductase activitydefinition[GO:0015035] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell redox homeostasisdefinition[GO:0045454] silver  
  • IEAInterPro 2 GO
Hemopoiesisdefinition[GO:0030097]  
  • ISSOrtholog Curator
Oxidation-reduction processdefinition[GO:0055114]  
  • IEAInterPro 2 GO
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GLRX5
GenomeRNAi: 51218
PRO: PR:Q86SX6