SLC51A - Organic solute transporter subunit alpha - human protein (Function)
 
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Protein
Gene
References

 
SLC51A »  Organic solute transporter subunit alpha  (OST-alpha)
 
Protein also known as:  Solute carrier family 51 subunit alpha.
Gene name:  SLC51A
Family name: OST-alpha
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the organic solute transporter (ost) family  2.A.82.1.2  
GO molecular function 
Protein heterodimerization activitydefinition[GO:0046982]  
  • ISSOrtholog Curator
Protein homodimerization activitydefinition[GO:0042803]  
  • ISSOrtholog Curator
Transporter activitydefinition[GO:0005215]  
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  • IDAUniProtKB
GO biological process 
Bile acid and bile salt transportdefinition[GO:0015721]  
  • ISSOrtholog Curator
Transportdefinition[GO:0006810]  
1
  • IEPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Bile secretion  hsa04976+200931  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: OSTalpha
GenomeRNAi: 200931
PRO: PR:Q86UW1