CADPS2 - Calcium-dependent secretion activator 2 - human protein (Function)
 
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CADPS2 »  Calcium-dependent secretion activator 2
 
Protein also known as:  Calcium-dependent activator protein for secretion 2 (CAPS-2).
Gene name:  CADPS2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Lipid bindingdefinition[GO:0008289]  
  • IEAUniProtKB KW
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
GO biological process 
Positive regulation of exocytosisdefinition[GO:0045921] silver  
  • IEAOrtholog Compara
Protein transportdefinition[GO:0015031]  
  • IEAUniProtKB KW
Synaptic vesicle primingdefinition[GO:0016082] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Exocytosis  definition   [KW-0268]
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CADPS2
GenomeRNAi: 93664
PRO: PR:Q86UW7