TXNDC2 - Thioredoxin domain-containing protein 2 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
TXNDC2 »  Thioredoxin domain-containing protein 2
 
Protein also known as:  Spermatid-specific thioredoxin-1 (Sptrx-1).
Gene name:  TXNDC2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 23 3
GENE REF ISO

Function

 show evidences
Overview 
Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.  
  • CuratedUniProtKB
GO molecular function 
Nutrient reservoir activitydefinition[GO:0045735] silver  
  • IEAInterPro 2 GO
Protein disulfide isomerase activitydefinition[GO:0003756] silver  
  • IEAOrtholog Compara
Protein disulfide oxidoreductase activitydefinition[GO:0015035] silver  
  • IEAInterPro 2 GO
Thioredoxin-disulfide reductase activitydefinition[GO:0004791]  
1
  • IDAUniProtKB
  • ISSOrtholog Curator
GO biological process 
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Cell redox homeostasisdefinition[GO:0045454]  
1
  • NASUniProtKB
Glycerol ether metabolic processdefinition[GO:0006662] silver  
  • IEAInterPro 2 GO
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Oxidation-reduction processdefinition[GO:0055114]  
1
  • IDAGOC
  • IEAInterPro 2 GO
  • ISSOrtholog Curator
Protein foldingdefinition[GO:0006457] silver  
  • IEAOrtholog Compara
Spermatogenesisdefinition[GO:0007283]  
1
  • NASUniProtKB
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Spermatogenesis  definition   [KW-0744]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TXNDC2
GenomeRNAi: 84203
PRO: PR:Q86VQ3