CATSPERD - Cation channel sperm-associated protein subunit delta - human protein (Function)
 
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Protein
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CATSPERD »  Cation channel sperm-associated protein subunit delta  (CatSperdelta)
 
Protein also known as:  Transmembrane protein 146.
Gene name:  CATSPERD
Family name: CATSPERD
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.19.1  
GO biological process 
Cilium or flagellum-dependent cell motilitydefinition[GO:0001539] silver  
  • IEAOrtholog Compara
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Sperm capacitationdefinition[GO:0048240]  
  • ISSOrtholog Curator
Sperm motilitydefinition[GO:0030317]  
  • ISSOrtholog Curator
Spermatogenesisdefinition[GO:0007283]  
  • ISSOrtholog Curator
Pathways 
According to Reactome, this protein belongs to the following pathway:
Reproduction  REACT_163848  
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Spermatogenesis  definition   [KW-0744]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 257062
PRO: PR:Q86XM0