COL23A1 - Collagen alpha-1(XXIII) chain - human protein (Sequence)
 
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Protein
Gene
References

 
COL23A1 »  Collagen alpha-1(XXIII) chain
 
Gene name:  COL23A1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 13 2
GENE REF ISO

Displayed isoform: Iso 1     

 
 
Isoform Iso 1   540 aaMass: 51944 Da,  pI: 6.88
MGPGERAGGG GDAGKGNAAG GGGGGRSATT AGSRAVSALC LLLSVGSAAA CLLLGVQAAA LQGRVAALEE ERELLRRAGP PGALDAWAEP HLERLLREKL DGLAKIRTAR EAPSECVCPP GPPGRRGKPG RRGDPGPPGQ SGRDGYPGPL GLDGKPGLPG PKGEKGAPGD FGPRGDQGQD GAAGPPGPPG PPGARGPPGD TGKDGPRGAQ GPAGPKGEPG QDGEMGPKGP PGPKGEPGVP GKKGDDGTPS QPGPPGPKGE PGSMGPRGEN GVDGAPGPKG EPGHRGTDGA AGPRGAPGLK GEQGDTVVID YDGRILDALK GPPGPQGPPG PPGIPGAKGE LGLPGAPGID GEKGPKGQKG DPGEPGPAGL KGEAGEMGLS GLPGADGLKG EKGESASDSL QESLAQLIVE PGPPGPPGPP GPMGLQGIQG PKGLDGAKGE KGASGERGPS GLPGPVGPPG LIGLPGTKGE KGRPGEPGLD GFPGPRGEKG DRSERGEKGE RGVPGRKGVK GQKGEPGPPG LDQPCPVGPD GLPVPGCWHK

Sequence

 show evidences
PTM 
Undergoes proteolytic cleavage by furin protease to yield a 60 kDa soluble form that forms a homotrimer and exhibits a low affinity interaction with heparin (By similarity).  
  • CuratedUniProtKB
 

Keywords

Coding sequence diversity 
Alternative splicing  definition   [KW-0025]
Polymorphism  definition   [KW-0621]
Domain 
Collagen  definition   [KW-0176]
Repeat  definition   [KW-0677]
Signal-anchor  definition   [KW-0735]
Transmembrane  definition   [KW-0812]
Transmembrane helix  definition   [KW-1133]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
InterPro: IPR008160 [ Collagen ]
Pfam: PF01391 [ Collagen ]
Genome annotation databases
Ensembl: Transcript: ENST00000390654;  Protein: ENSP00000375069;  Gene: ENSG00000050767.
Ensembl: Transcript: ENST00000407622;  Protein: ENSP00000385092;  Gene: ENSG00000050767.
KEGG: hsa:91522
UCSC: uc021yiy.1
Organism-specific databases
MGI: MGI:2653243 [ Col23a1 ]
PTM databases
PhosphoSite: Q86Y22
Phylogenomic databases
eggNOG: NOG320189
HOGENOM: HOG000085653
HOVERGEN: HBG004933
InParanoid: Q86Y22
OMA: IPGRKGV
OrthoDB: EOG7D59P1
PhylomeDB: Q86Y22
TreeFam: TF338175
Sequence databases
CCDS: CCDS4436.1 [ Q86Y22-1 ]
EMBL: mRNA:  BC042428 . Translation:  AAH42428.1 .
EMBL: mRNA:  AY158895 . Translation:  AAO18361.1 .
EMBL: mRNA:  AL137461 . Translation:  CAB70749.1 .
EMBL: mRNA:  AY898961 . Translation:  AAX84028.1 .
PIR: T46404
RefSeq: Protein:  NP_775736.2. Nucleotide sequence:  NM_173465.3.
UniProtKB: Q86Y22 [ COL23A1 ]