STX12 - Syntaxin-12 - human protein (Function)
 
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Protein
Gene
References

 
STX12 »  Syntaxin-12
 
Gene name:  STX12
Family name: Syntaxin
Entry whose protein(s) existence is based on evidence at protein level
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1 23 1
GENE REF ISO

Function

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Overview 
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
3
  • IPIUniProtKB
  • IPIBHF-UCL
SNAP receptor activitydefinition[GO:0005484] silver  
  • IBARefGenome
SNARE bindingdefinition[GO:0000149] silver  
  • IBARefGenome
GO biological process 
Cholesterol effluxdefinition[GO:0033344]  
1
  • IDABHF-UCL
Intracellular protein transportdefinition[GO:0006886] silver  
  • IBARefGenome
Protein stabilizationdefinition[GO:0050821]  
1
  • IDABHF-UCL
Synaptic vesicle exocytosisdefinition[GO:0016079] silver  
  • IBARefGenome
Pathways 
According to KEGG, this protein belongs to the following pathway:
Phagosome  hsa04145+23673  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Neuronal System  REACT_13685  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: STX12
GenomeRNAi: 23673
PRO: PR:Q86Y82