RAB11FIP4 - Rab11 family-interacting protein 4 - human protein (Function)
 
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Protein
Gene
References

 
RAB11FIP4 »  Rab11 family-interacting protein 4  (FIP4-Rab11)
 
Protein also known as:  Arfophilin-2.
Gene name:  RAB11FIP4
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 32 2
GENE REF ISO

Function

 show evidences
Overview 
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.  
2
  • UniProtKB
GO molecular function 
ADP-ribosylation factor bindingdefinition[GO:0030306]  
1
  • UniProtKB
Calcium ion bindingdefinition[GO:0005509] silver  
1
  • InterPro 2 GO
Protein bindingdefinition[GO:0005515]  
4
  • IntAct
  • UniProtKB
Protein homodimerization activitydefinition[GO:0042803]  
1
  • UniProtKB
Rab GTPase bindingdefinition[GO:0017137]  
2
  • UniProtKB
GO biological process 
Cytokinesisdefinition[GO:0000910]  
1
  • UniProtKB
Transportdefinition[GO:0006810]  
1
  • UniProtKB KW
Viral processdefinition[GO:0016032]  
1
  • UniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Endocytosis  hsa04144+84440  
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RAB11FIP4
GenomeRNAi: 84440
PRO: PR:Q86YS3