SLC13A5 - Solute carrier family 13 member 5 - human protein (Function)
 
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Protein
Gene
References

 
SLC13A5 »  Solute carrier family 13 member 5
 
Protein also known as:  Sodium-dependent citrate transporter.
Gene name:  SLC13A5
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 18 2
GENE REF ISO

Function

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Overview 
High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the divalent anion:na(+) symporter (dass) family  2.A.47.1.9  
GO molecular function 
Citrate transmembrane transporter activitydefinition[GO:0015137] silver  
  • IEAOrtholog Compara
Sodium:dicarboxylate symporter activitydefinition[GO:0017153] silver  
  • IEAOrtholog Compara
Succinate transmembrane transporter activitydefinition[GO:0015141] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathways:
Bile salt and organic anion SLC transporters  REACT_20633  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 284111
PRO: PR:Q86YT5