KSR1 - Kinase suppressor of Ras 1 - human protein (Function)
 
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Protein
Gene
References

 
KSR1 »  Kinase suppressor of Ras 1
 
Gene name:  KSR1
Entry whose protein(s) existence is based on evidence at protein level
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1 45 3
GENE REF ISO

Function

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Overview 
Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524] silver  
  • IEAInterPro 2 GO
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Protein kinase activitydefinition[GO:0004672]  
1
  • NASUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674] silver  
  • IEAInterPro 2 GO
GO biological process 
Ras protein signal transductiondefinition[GO:0007265]  
1
  • NASUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Tuberculosis  hsa05152+8844  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KSR1
GenomeRNAi: 8844
PRO: PR:Q8IVT5