ARHGEF19 - Rho guanine nucleotide exchange factor 19 - human protein (Function)
 
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Protein
Gene
References

 
ARHGEF19 »  Rho guanine nucleotide exchange factor 19
 
Protein also known as:  Ephexin-2.
Gene name:  ARHGEF19
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase (By similarity).  
  • CuratedUniProtKB
GO molecular function 
GTPase activator activitydefinition[GO:0005096]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Rho guanyl-nucleotide exchange factor activitydefinition[GO:0005089] silver  
  • IEAInterPro 2 GO
GO biological process 
Positive regulation of Rho GTPase activitydefinition[GO:0032321] silver  
  • IEAOrtholog Compara
Regulation of actin cytoskeleton organizationdefinition[GO:0032956]  
1
  • IGIMGI
Wound healingdefinition[GO:0042060] silver  
  • IEAOrtholog Compara
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Guanine-nucleotide releasing factor  definition   [KW-0344]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 128272
PRO: PR:Q8IW93