LMTK2 - Serine/threonine-protein kinase LMTK2 - human protein (Function)
 
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LMTK2 »  Serine/threonine-protein kinase LMTK2   [ EC 2.7.11.1 ]
 
Protein also known as:  Apoptosis-associated tyrosine kinase 2.
Gene name:  LMTK2
Entry whose protein(s) existence is based on evidence at protein level
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1 39 1
GENE REF ISO

Function

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Overview 
Phosphorylates PPP1C, phosphorylase b and CFTR.  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • NASUniProtKB
Myosin VI bindingdefinition[GO:0070853]  
2
  • IPIUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
  • IPIIntAct
Protein phosphatase inhibitor activitydefinition[GO:0004864]  
1
  • IDAUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674]  
2
  • IDAUniProtKB
Protein tyrosine kinase activitydefinition[GO:0004713] silver  
  • IEAInterPro 2 GO
GO biological process 
Early endosome to late endosome transportdefinition[GO:0045022]  
1
  • IMPUniProtKB
Endocytic recyclingdefinition[GO:0032456]  
1
  • IMPUniProtKB
Negative regulation of catalytic activitydefinition[GO:0043086]  
1
  • IDAGOC
Peptidyl-serine phosphorylationdefinition[GO:0018105]  
1
  • IDAUniProtKB
Peptidyl-threonine phosphorylationdefinition[GO:0018107]  
1
  • IDAUniProtKB
Protein autophosphorylationdefinition[GO:0046777]  
1
  • IDAUniProtKB
Protein phosphorylationdefinition[GO:0006468]  
1
  • IDAUniProtKB
Receptor recyclingdefinition[GO:0001881]  
2
  • IMPUniProtKB
Regulation of catalytic activitydefinition[GO:0050790]  
1
  • IDAGOC
Transferrin transportdefinition[GO:0033572]  
2
  • IMPUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LMTK2
GenomeRNAi: 22853
PRO: PR:Q8IWU2