ARHGAP12 - Rho GTPase-activating protein 12 - human protein (Function)
 
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Protein
Gene
References

 
ARHGAP12 »  Rho GTPase-activating protein 12
 
Gene name:  ARHGAP12
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity).  
  • CuratedUniProtKB
GO molecular function 
GTPase activator activitydefinition[GO:0005096]  
  • IEAUniProtKB KW
GO biological process 
Morphogenesis of an epithelial sheetdefinition[GO:0002011]  
1
  • IMPUniProtKB
Positive regulation of GTPase activitydefinition[GO:0043547]  
  • IEAUniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathway:
Rho GTPase cycle  REACT_11051  
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 94134
PRO: PR:Q8IWW6