MRPL41 - 39S ribosomal protein L41, mitochondrial - human protein (Function)
 
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MRPL41 »  39S ribosomal protein L41, mitochondrial  (L41mt)
 
Protein also known as:  Bcl-2-interacting mitochondrial ribosomal protein L41.
Gene name:  MRPL41
Family name: Ribosomal protein L41
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.  
2
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Structural constituent of ribosomedefinition[GO:0003735]  
1
  • IDAUniProtKB
GO biological process 
Apoptotic processdefinition[GO:0006915]  
  • IEAUniProtKB KW
Cell cycledefinition[GO:0007049]  
  • IEAUniProtKB KW
Translationdefinition[GO:0006412]  
1
  • IDAUniProtKB
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Cell cycle  definition   [KW-0131]
Molecular function 
Ribonucleoprotein  definition   [KW-0687]
Ribosomal protein  definition   [KW-0689]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links