NOXIN - Nitric oxide-inducible gene protein - human protein (Function)
 
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Protein
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References

 
NOXIN »  Nitric oxide-inducible gene protein
 
Gene name:  NOXIN
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Acts as an anti-apoptotic factor and its absence increases cell death under normal and stress conditions. Can induce cell cycle arrest in the G1 or early S phase and this activity is independent of p53/TP53 (By similarity).  
  • CuratedUniProtKB
GO biological process 
Apoptotic processdefinition[GO:0006915]  
  • IEAUniProtKB KW
Cellular response to cytokine stimulusdefinition[GO:0071345] silver  
  • IEAOrtholog Compara
Cellular response to DNA damage stimulusdefinition[GO:0006974] silver  
  • IEAOrtholog Compara
Cellular response to gamma radiationdefinition[GO:0071480] silver  
  • IEAOrtholog Compara
Cellular response to hydroperoxidedefinition[GO:0071447] silver  
  • IEAOrtholog Compara
Cellular response to UVdefinition[GO:0034644] silver  
  • IEAOrtholog Compara
Hemopoiesisdefinition[GO:0030097] silver  
  • IEAOrtholog Compara
Mitotic cell cycle arrestdefinition[GO:0071850] silver  
  • IEAOrtholog Compara
Negative regulation of fibroblast apoptotic processdefinition[GO:2000270] silver  
  • IEAOrtholog Compara
Spermatid developmentdefinition[GO:0007286] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Cell cycle  definition   [KW-0131]
Growth arrest  definition   [KW-0338]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 220042
PRO: PR:Q8IXT1