VPS52 - Vacuolar protein sorting-associated protein 52 homolog - human protein (Function)
 
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VPS52 »  Vacuolar protein sorting-associated protein 52 homolog
 
Protein also known as:  SAC2 suppressor of actin mutations 2-like protein.
Gene name:  VPS52
Family name: VPS52
Entry whose protein(s) existence is based on evidence at protein level
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1 21 1
GENE REF ISO

Function

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Overview 
May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  
2
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
  • IPIIntAct
GO biological process 
Ectodermal cell differentiationdefinition[GO:0010668] silver  
  • IEAOrtholog Compara
Embryonic ectodermal digestive tract developmentdefinition[GO:0048611] silver  
  • IEAOrtholog Compara
Protein transportdefinition[GO:0015031]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: VPS52
GenomeRNAi: 6293
PRO: PR:Q8N1B4