NUP93 - Nuclear pore complex protein Nup93 - human protein (Function)
 
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NUP93 »  Nuclear pore complex protein Nup93
 
Protein also known as:  93 kDa nucleoporin.
Gene name:  NUP93
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.  
3
  • UniProtKB
According to TCDB this is a transporter from family:
the nuclear pore complex (npc) family  1.I.1.1.3  
GO molecular function 
Structural constituent of nuclear poredefinition[GO:0017056]  
1
  • UniProtKB
GO biological process 
Mitophagy in response to mitochondrial depolarizationdefinition[GO:0098779]  
1
  • ParkinsonsUK-UCL
Nuclear pore complex assemblydefinition[GO:0051292]  
1
  • UniProtKB
Poly(A)+ mRNA export from nucleusdefinition[GO:0016973]  
1
  • RefGenome
Positive regulation of defense response to virus by hostdefinition[GO:0002230]  
1
  • ParkinsonsUK-UCL
Protein import into nucleusdefinition[GO:0006606]  
1
  • RefGenome
Xenophagydefinition[GO:0098792]  
1
  • ParkinsonsUK-UCL
Pathways 
According to KEGG, this protein belongs to the following pathway:
RNA transport  hsa03013+9688  
According to Reactome, this protein belongs to the following pathways:
ISG15 antiviral mechanism  R-HSA-1169408  
NS1 Mediated Effects on Host Pathways  R-HSA-168276  
Nuclear import of Rev protein  R-HSA-180746  
Nuclear Pore Complex (NPC) Disassembly  R-HSA-3301854  
Regulation of Glucokinase by Glucokinase Regulatory Protein  R-HSA-170822  
Regulation of HSF1-mediated heat shock response  R-HSA-3371453  
Rev-mediated nuclear export of HIV RNA  R-HSA-165054  
SUMOylation of DNA damage response and repair proteins  R-HSA-3108214  
Transcriptional regulation by small RNAs  R-HSA-5578749  
tRNA processing in the nucleus  R-HSA-6784531  
Viral Messenger RNA Synthesis  R-HSA-168325  
Vpr-mediated nuclear import of PICs  R-HSA-180910  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Translocation  definition   [KW-0811]
Transport  definition   [KW-0813]
mRNA transport  definition   [KW-0509]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NUP93
GenomeRNAi: 9688
PRO: PR:Q8N1F7