BEST3 - Bestrophin-3 - human protein (Function)
 
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Protein
Gene
References

 
BEST3 »  Bestrophin-3
 
Protein also known as:  Vitelliform macular dystrophy 2-like protein 3.
Gene name:  BEST3
Family name: Bestrophin
Entry whose protein(s) existence is based on evidence at transcript level
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1 25 4
GENE REF ISO

Function

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Overview 
Forms calcium-sensitive (By similarity) chloride channels. Permeable to bicarbonate (By similarity).  
1
  • CuratedUniProtKB
GO molecular function 
Chloride channel activitydefinition[GO:0005254] silver  
  • IEAOrtholog Compara
GO biological process 
Negative regulation of ion transportdefinition[GO:0043271] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Molecular function 
Chloride channel  definition   [KW-0869]
Ion channel  definition   [KW-0407]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 144453
PRO: PR:Q8N1M1