NIN - Ninein - human protein (Function)
 
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Protein
Gene
References

 
NIN »  Ninein
 
Protein also known as:  Glycogen synthase kinase 3 beta-interacting protein (GSK3B-interacting protein).
Gene name:  NIN
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells. May also act as a centrosome maturation factor. May play a role in microtubule nucleation. Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules.  
1
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
GTP bindingdefinition[GO:0005525]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
6
  • IPIUniProtKB
  • IPIIntAct
  • IPIHGNC
GO biological process 
Centrosome localizationdefinition[GO:0051642]  
1
  • TASHGNC
Centrosome-templated microtubule nucleationdefinition[GO:0090222] silver  
  • IEAOrtholog Compara
Microtubule anchoring at centrosomedefinition[GO:0034454] silver  
  • IEAOrtholog Compara
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NIN_(gene)
GenomeRNAi: 51199
PRO: PR:Q8N4C6