CLDN19 - Claudin-19 - human protein (Function)
 
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Protein
Gene
References

 
CLDN19 »  Claudin-19
 
Gene name:  CLDN19
Family name: Claudin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the claudin tight junction (claudin) family  1.H.1.1.5  
GO molecular function 
Identical protein bindingdefinition[GO:0042802]  
  • ISSOrtholog Curator
Structural molecule activitydefinition[GO:0005198] silver  
  • IEAOrtholog Compara
GO biological process 
Apical junction assemblydefinition[GO:0043297] silver  
  • IEAOrtholog Compara
Calcium-independent cell-cell adhesiondefinition[GO:0016338]  
  • ISSOrtholog Curator
Neuronal action potential propagationdefinition[GO:0019227] silver  
  • IEAOrtholog Compara
Response to stimulusdefinition[GO:0050896]  
  • IEAUniProtKB KW
Visual perceptiondefinition[GO:0007601]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cell adhesion molecules (CAMs)  hsa04514+149461  
Hepatitis C  hsa05160+149461  
Leukocyte transendothelial migration  hsa04670+149461  
Tight junction  hsa04530+149461  
According to Reactome, this protein belongs to the following pathway:
Cell-Cell communication  REACT_111155  
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Vision  definition   [KW-0844]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CLDN19
GenomeRNAi: 149461
PRO: PR:Q8N6F1