CSNK1A1L - Casein kinase I isoform alpha-like - human protein (Function)
 
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CSNK1A1L »  Casein kinase I isoform alpha-like   [ EC 2.7.11.1 ]  (CKI-alpha-like)
 
Protein also known as:  CK1.
Gene name:  CSNK1A1L
Entry whose protein(s) existence is based on evidence at protein level
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1 18 1
GENE REF ISO

Function

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Overview 
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Protein serine/threonine kinase activitydefinition[GO:0004674]  
  • IEAUniProtKB KW
GO biological process 
Protein phosphorylationdefinition[GO:0006468] silver  
  • IEAInterPro 2 GO
Wnt signaling pathwaydefinition[GO:0016055]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Hedgehog signaling pathway  hsa04340+122011  
Wnt signaling pathway  hsa04310+122011  
 

Keywords

Biological process 
Wnt signaling pathway  definition   [KW-0879]
Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GenomeRNAi: 122011
PRO: PR:Q8N752
Chemistry
GuidetoPHARMACOLOGY: 1996