CLDN22 - Claudin-22 - human protein (Function)
 
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Protein
Gene
References

 
CLDN22 »  Claudin-22
 
Gene name:  CLDN22
Family name: Claudin
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the claudin tight junction (claudin) family  1.H.1.1.3  
GO molecular function 
Identical protein bindingdefinition[GO:0042802]  
  • ISSOrtholog Curator
Structural molecule activitydefinition[GO:0005198] silver  
  • IEAInterPro 2 GO
GO biological process 
Calcium-independent cell-cell adhesiondefinition[GO:0016338]  
  • ISSOrtholog Curator
Pathways 
According to KEGG, this protein belongs to the following pathways:
Cell adhesion molecules (CAMs)  hsa04514+53842  
Hepatitis C  hsa05160+53842  
Leukocyte transendothelial migration  hsa04670+53842  
Tight junction  hsa04530+53842  
According to Reactome, this protein belongs to the following pathway:
Cell-Cell communication  REACT_111155  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CLDN22
GenomeRNAi: 53842
PRO: PR:Q8N7P3