KDF1 - Keratinocyte differentiation factor 1 - human protein (Function)
 
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Protein
Gene
References

 
KDF1 »  Keratinocyte differentiation factor 1
 
Gene name:  KDF1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).  
1
  • UniProtKB
GO biological process 
Developmental growthdefinition[GO:0048589]  
1
  • Ortholog Curator
Establishment of skin barrierdefinition[GO:0061436]  
1
  • Ortholog Curator
Keratinocyte developmentdefinition[GO:0003334] silver  
1
  • Ortholog Compara
Limb epidermis developmentdefinition[GO:0060887]  
1
  • Ortholog Curator
Morphogenesis of embryonic epitheliumdefinition[GO:0016331]  
1
  • Ortholog Curator
Negative regulation of keratinocyte proliferationdefinition[GO:0010839] silver  
1
  • Ortholog Compara
Negative regulation of stem cell proliferationdefinition[GO:2000647]  
1
  • Ortholog Curator
Positive regulation of epidermal cell differentiationdefinition[GO:0045606]  
1
  • Ortholog Curator
Regulation of epidermal cell divisiondefinition[GO:0010482]  
1
  • Ortholog Curator
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 126695