BHLHE23 - Class E basic helix-loop-helix protein 23 - human protein (Function)
 
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Protein
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BHLHE23 »  Class E basic helix-loop-helix protein 23
 
Gene name:  BHLHE23
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
May function as transcriptional repressor. May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and neuronal cell types. May be important for rod bipolar cell maturation (By similarity).  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
Protein dimerization activitydefinition[GO:0046983] silver  
  • IEAInterPro 2 GO
GO biological process 
Negative regulation of retinal cell programmed cell deathdefinition[GO:0046671] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Post-embryonic eye morphogenesisdefinition[GO:0048050] silver  
  • IEAOrtholog Compara
Retinal rod cell developmentdefinition[GO:0046548] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links