MYO3A - Myosin-IIIa - human protein (Function)
 
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MYO3A »  Myosin-IIIa   [ EC 2.7.11.1 ]
 
Gene name:  MYO3A
Family name: In the N-terminal section Protein kinase » STE Ser/Thr protein kinase
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing.  
1
  • CuratedUniProtKB
GO molecular function 
Actin filament bindingdefinition[GO:0051015] silver  
  • IEAOrtholog Compara
Actin-dependent ATPase activitydefinition[GO:0030898]  
1
  • IDAUniProtKB
ADP bindingdefinition[GO:0043531]  
1
  • IDAUniProtKB
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Calmodulin bindingdefinition[GO:0005516]  
1
  • IDAUniProtKB
Microfilament motor activitydefinition[GO:0000146]  
2
  • IMPUniProtKB
Plus-end directed microfilament motor activitydefinition[GO:0060002]  
1
  • IDAUniProtKB
Protein kinase activitydefinition[GO:0004672]  
1
  • IDAUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674] silver  
  • IEAOrtholog Compara
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
1
  • IDAGOC
Inner ear developmentdefinition[GO:0048839] silver  
  • IEAOrtholog Compara
Peptidyl-serine phosphorylationdefinition[GO:0018105] silver  
  • IEAOrtholog Compara
Peptidyl-threonine phosphorylationdefinition[GO:0018107] silver  
  • IEAOrtholog Compara
Positive regulation of filopodium assemblydefinition[GO:0051491] silver  
  • IEAOrtholog Compara
Protein autophosphorylationdefinition[GO:0046777]  
1
  • IDAUniProtKB
Response to stimulusdefinition[GO:0050896]  
  • IEAUniProtKB KW
Sensory perception of sounddefinition[GO:0007605]  
1
  • IMPUniProtKB
Visual perceptiondefinition[GO:0007601]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Hearing  definition   [KW-1009]
Sensory transduction  definition   [KW-0716]
Vision  definition   [KW-0844]
Molecular function 
Kinase  definition   [KW-0418]
Motor protein  definition   [KW-0505]
Myosin  definition   [KW-0518]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: MYO3A
GenomeRNAi: 53904
PRO: PR:Q8NEV4
Chemistry
GuidetoPHARMACOLOGY: 2112