RXFP4 - Relaxin-3 receptor 2 - human protein (Function)
 
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Protein
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References

 
RXFP4 »  Relaxin-3 receptor 2  (RLN3 receptor 2)
 
Protein also known as:  Insulin-like peptide INSL5 receptor.
Gene name:  RXFP4
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 18 1
GENE REF ISO

Function

 show evidences
Overview 
High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.  
2
  • CuratedUniProtKB
GO molecular function 
Angiotensin type II receptor activitydefinition[GO:0004945] silver  
  • IEAInterPro 2 GO
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Angiotensin-activated signaling pathwaydefinition[GO:0038166]  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathways:
G alpha (i) signalling events  REACT_19231  
Relaxin receptors  REACT_21314  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Relaxin/insulin-like_family_peptide_receptor_4
GenomeRNAi: 339403
PRO: PR:Q8TDU9
Chemistry
GuidetoPHARMACOLOGY: 354