GPR119 - Glucose-dependent insulinotropic receptor - human protein (Function)
 
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GPR119 »  Glucose-dependent insulinotropic receptor
 
Protein also known as:  G-protein coupled receptor 119.
Gene name:  GPR119
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.  
1
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
Phosphatidylcholine bindingdefinition[GO:0031210] silver  
  • IEAOrtholog Compara
GO biological process 
Insulin secretiondefinition[GO:0030073] silver  
  • IEAOrtholog Compara
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: GPR119
GenomeRNAi: 139760
PRO: PR:Q8TDV5
Chemistry
GuidetoPHARMACOLOGY: 126