PIGO - GPI ethanolamine phosphate transferase 3 - human protein (Function)
 
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Protein
Gene
References

 
PIGO »  GPI ethanolamine phosphate transferase 3   [ EC 2.-.-.- ]
 
Protein also known as:  Phosphatidylinositol-glycan biosynthesis class O protein (PIG-O).
Gene name:  PIGO
Family name: PIGG/PIGN/PIGO » PIGO
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Transferase activitydefinition[GO:0016740]  
  • IEAUniProtKB KW
GO biological process 
GPI anchor biosynthetic processdefinition[GO:0006506]  
  • ISSOrtholog Curator
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis  hsa00563+84720  
Metabolic pathways  hsa01100+84720  
According to Reactome, this protein belongs to the following pathway:
Metabolism of proteins  REACT_17015  
 

Keywords

Biological process 
GPI-anchor biosynthesis  definition   [KW-0337]
Molecular function 
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 84720
PRO: PR:Q8TEQ8