IP6K1 - Inositol hexakisphosphate kinase 1 - human protein (Function)
 
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IP6K1 »  Inositol hexakisphosphate kinase 1   [ EC 2.7.4.21 ]  (InsP6 kinase 1)
 
Protein also known as:  Inositol hexaphosphate kinase 1.
Gene name:  IP6K1
Entry whose protein(s) existence is based on evidence at protein level
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1 23 2
GENE REF ISO

Function

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Overview 
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Inositol hexakisphosphate 1-kinase activitydefinition[GO:0052723]  
  • IEAEC 2 GO
Inositol hexakisphosphate 3-kinase activitydefinition[GO:0052724]  
  • IEAEC 2 GO
Inositol hexakisphosphate 5-kinase activitydefinition[GO:0000832]  
  • IEAEC 2 GO
Inositol-1,4,5-trisphosphate 3-kinase activitydefinition[GO:0008440] silver  
  • IEAInterPro 2 GO
GO biological process 
Phosphatidylinositol phosphorylationdefinition[GO:0046854]  
1
  • IDAUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reactions
ATP + 1D-myo-inositol hexakisphosphate ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate.  
  • CuratedUniProtKB
ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate.  
  • CuratedUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 
More information is available from:
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: IHPK1
GenomeRNAi: 9807
PRO: PR:Q92551