JADE3 - Protein Jade-3 - human protein (Function)
 
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Protein
Gene
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JADE3 »  Protein Jade-3
 
Protein also known as:  Jade family PHD finger protein 3.
Gene name:  JADE3
Family name: JADE
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.  
2
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Zinc ion bindingdefinition[GO:0008270] silver  
1
  • InterPro 2 GO
GO biological process 
Histone H3 acetylationdefinition[GO:0043966]  
1
  • UniProtKB
Histone H4-K12 acetylationdefinition[GO:0043983]  
1
  • UniProtKB
Not  Histone H4-K16 acetylationdefinition[GO:0043984]  
1
  • UniProtKB
Histone H4-K5 acetylationdefinition[GO:0043981]  
1
  • UniProtKB
Histone H4-K8 acetylationdefinition[GO:0043982]  
1
  • UniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
HATs acetylate histones  REACT_264245  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PHF16
GenomeRNAi: 9767
PRO: PR:Q92613