KCNJ9 - G protein-activated inward rectifier potassium channel 3 - human protein (Function)
 
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Protein
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References

 
KCNJ9 »  G protein-activated inward rectifier potassium channel 3  (GIRK-3)
 
Protein also known as:  Potassium channel, inwardly rectifying subfamily J member 9.
Gene name:  KCNJ9
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 17 1
GENE REF ISO

Function

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Overview 
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).  
  • CuratedUniProtKB
GO molecular function 
G-protein activated inward rectifier potassium channel activitydefinition[GO:0015467] silver  
  • IEAInterPro 2 GO
PDZ domain bindingdefinition[GO:0030165] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
1
  • IPIBHF-UCL
Pathways 
According to KEGG, this protein belongs to the following pathway:
Dopaminergic synapse  hsa04728+3765  
According to Reactome, this protein belongs to the following pathway:
Neuronal System  REACT_13685  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNJ9
GenomeRNAi: 3765
PRO: PR:Q92806
Chemistry
GuidetoPHARMACOLOGY: 436