SMARCD2 - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 - human protein (Function)
 
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SMARCD2 »  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
 
Protein also known as:  60 kDa BRG-1/Brm-associated factor subunit B.
Gene name:  SMARCD2
Family name: SMARCD
Entry whose protein(s) existence is based on evidence at protein level
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1 28 3
GENE REF ISO

Function

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Overview 
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).  
  • CuratedUniProtKB
GO molecular function 
Contributes to nucleosomal DNA bindingdefinition[GO:0031492]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Contributes to RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978]  
1
  • IDAUniProtKB
Contributes to RNA polymerase II distal enhancer sequence-specific DNA bindingdefinition[GO:0000980]  
1
  • IDAUniProtKB
Transcription coactivator activitydefinition[GO:0003713]  
1
  • NASUniProtKB
GO biological process 
ATP-dependent chromatin remodelingdefinition[GO:0043044]  
1
  • IDAUniProtKB
Chromatin remodelingdefinition[GO:0006338]  
1
  • IDABHF-UCL
Nucleosome disassemblydefinition[GO:0006337]  
1
  • IDABHF-UCL
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • NASUniProtKB
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Chromatin regulator  definition   [KW-0156]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SMARCD2
GenomeRNAi: 6603
PRO: PR:Q92925