FOXJ1 - Forkhead box protein J1 - human protein (Function)
 
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Protein
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References

 
FOXJ1 »  Forkhead box protein J1
 
Protein also known as:  Hepatocyte nuclear factor 3 forkhead homolog 4 (HFH-4).
Gene name:  FOXJ1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

 show evidences
Overview 
May play an important role in cell fate determination during lung development and in spermatogenesis (By similarity).  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • NASUniProtKB
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • NASUniProtKB
Transcription regulatory region sequence-specific DNA bindingdefinition[GO:0000976]  
1
  • IDABHF-UCL
GO biological process 
Actin cytoskeleton organizationdefinition[GO:0030036]  
  • ISSOrtholog Curator
Activation of Rho GTPase activitydefinition[GO:0032862]  
  • ISSOrtholog Curator
Brain developmentdefinition[GO:0007420]  
2
  • NASBHF-UCL
Central tolerance inductiondefinition[GO:0002508]  
  • ISSOrtholog Curator
Cilium assemblydefinition[GO:0042384]  
  • ISSOrtholog Curator
Epithelium developmentdefinition[GO:0060429]  
1
  • ISSBHF-UCL
Establishment of apical/basal cell polaritydefinition[GO:0035089]  
  • ISSOrtholog Curator
Glomerular parietal epithelial cell developmentdefinition[GO:0072016]  
1
  • IEPBHF-UCL
Humoral immune responsedefinition[GO:0006959]  
  • ISSOrtholog Curator
Left/right pattern formationdefinition[GO:0060972] silver  
  • IEAOrtholog Compara
Leukocyte migrationdefinition[GO:0050900]  
  • ISSOrtholog Curator
Lung epithelium developmentdefinition[GO:0060428]  
2
  • IEPBHF-UCL
Metanephric part of ureteric bud developmentdefinition[GO:0035502]  
1
  • IEPBHF-UCL
Negative regulation of B cell activationdefinition[GO:0050869]  
  • ISSOrtholog Curator
Negative regulation of germinal center formationdefinition[GO:0002635]  
  • ISSOrtholog Curator
Negative regulation of humoral immune response mediated by circulating immunoglobulindefinition[GO:0002924]  
  • ISSOrtholog Curator
Negative regulation of interleukin-6 biosynthetic processdefinition[GO:0045409]  
  • ISSOrtholog Curator
Negative regulation of NF-kappaB transcription factor activitydefinition[GO:0032088]  
  • ISSOrtholog Curator
Negative regulation of T cell differentiation in thymusdefinition[GO:0033085]  
  • ISSOrtholog Curator
Negative regulation of T cell proliferationdefinition[GO:0042130] silver  
  • IEAOrtholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
  • ISSOrtholog Curator
Pattern specification processdefinition[GO:0007389]  
  • ISSOrtholog Curator
Positive regulation of central B cell tolerance inductiondefinition[GO:0002897]  
  • ISSOrtholog Curator
Positive regulation of lung ciliated cell differentiationdefinition[GO:1901248]  
1
  • IDABHF-UCL
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • IDABHF-UCL
Spermatogenesisdefinition[GO:0007283]  
1
  • NASUniProtKB
Transcription from RNA polymerase II promoterdefinition[GO:0006366] silver  
  • IBARefGenome
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FOXJ1
GenomeRNAi: 2302
PRO: PR:Q92949