CLUAP1 - Clusterin-associated protein 1 - human protein (Function)
 
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Protein
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References

 
CLUAP1 »  Clusterin-associated protein 1
 
Protein also known as:  Qilin.
Gene name:  CLUAP1
Family name: CLUAP1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Cell projection organizationdefinition[GO:0030030]  
  • IEAUniProtKB KW
Note 
Associated with a number of cancers such as colon (PubMed15480429) and bone cancer (PubMed17203229). Possibly involved in polycystic kidney diseases (PubMed15530380).  
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  • CuratedUniProtKB
 

Keywords

Biological process 
Cilium biogenesis/degradation  definition   [KW-0970]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CLUAP1
GenomeRNAi: 23059
PRO: PR:Q96AJ1