CLUAP1 - Clusterin-associated protein 1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Protein
Gene
References

 
CLUAP1 »  Clusterin-associated protein 1
 
Protein also known as:  Qilin.
Gene name:  CLUAP1
Family name: CLUAP1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 16 2
GENE REF ISO

Function

 show evidences
Overview 
Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity).  
1
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
2
  • IntAct
GO biological process 
Cilium assemblydefinition[GO:0042384]  
1
  • RefGenome
Pathways 
According to Reactome, this protein belongs to the following pathway:
Intraflagellar transport  REACT_268024  
Note 
Associated with a number of cancers such as colon (PubMed15480429) and bone cancer (PubMed17203229). Possibly involved in polycystic kidney diseases (PubMed15530380).  
4
  • UniProtKB
 

Keywords

Biological process 
Cilium biogenesis/degradation  definition   [KW-0970]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CLUAP1
GenomeRNAi: 23059
PRO: PR:Q96AJ1