SLAMF6 - SLAM family member 6 - human protein (Function)
 
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Protein
Gene
References

 
SLAMF6 »  SLAM family member 6
 
Protein also known as:  Activating NK receptor; CD antigen CD352.
Gene name:  SLAMF6
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.  
2
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
GO biological process 
Positive regulation of interferon-gamma productiondefinition[GO:0032729]  
1
  • UniProtKB
Positive regulation of interleukin-17 productiondefinition[GO:0032740]  
1
  • UniProtKB
Positive regulation of natural killer cell mediated cytotoxicitydefinition[GO:0045954]  
1
  • UniProtKB
T-helper 17 cell lineage commitmentdefinition[GO:0072540]  
1
  • UniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell  R-HSA-198933  
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLAMF6
GenomeRNAi: 114836
PRO: PR:Q96DU3