KIAA1279 - KIF1-binding protein - human protein (Function)
 
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KIAA1279 »  KIF1-binding protein
 
Gene name:  KIAA1279
Family name: KIF1-binding protein
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.  
3
  • CuratedUniProtKB
GO molecular function 
Kinesin bindingdefinition[GO:0019894]  
1
  • IPIUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Mitochondrial transportdefinition[GO:0006839]  
1
  • IMPUniProtKB
Nervous system developmentdefinition[GO:0007399]  
  • IEAUniProtKB KW
Caution 
Was originally shown to localize in the mitochondrion and to play a role in mitochondrial transport (PubMed16225668). Recent articles, however, have shown that it does not localize to mitochondria, it interacts with the cytoskeleton and does not have a role in mitochondrial function (PubMed20621975, PubMed23427148).  
3
  • CuratedUniProtKB
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KIAA1279
GenomeRNAi: 26128