BSCL2 - Seipin - human protein (Function)
 
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Protein
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BSCL2 »  Seipin
 
Protein also known as:  Bernardinelli-Seip congenital lipodystrophy type 2 protein.
Gene name:  BSCL2
Family name: Seipin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues.  
3
  • UniProtKB
GO biological process 
Fat cell differentiationdefinition[GO:0045444]  
1
  • Ortholog Curator
Lipid catabolic processdefinition[GO:0016042]  
1
  • UniProtKB KW
Lipid particle organizationdefinition[GO:0034389]  
1
  • UniProtKB
Lipid storagedefinition[GO:0019915]  
1
  • UniProtKB
Negative regulation of lipid catabolic processdefinition[GO:0050995]  
1
  • Ortholog Curator
 

Keywords

Biological process 
Lipid degradation  definition   [KW-0442]
Lipid metabolism  definition   [KW-0443]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BSCL2
GenomeRNAi: 26580
PRO: PR:Q96G97