MAP6 - Microtubule-associated protein 6 - human protein (Function)
 
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MAP6 »  Microtubule-associated protein 6  (MAP-6)
 
Protein also known as:  Stable tubule-only polypeptide (STOP).
Gene name:  MAP6
Family name: STOP
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B.  
2
  • UniProtKB
GO molecular function 
Calmodulin bindingdefinition[GO:0005516]  
1
  • UniProtKB KW
Microtubule bindingdefinition[GO:0008017] silver  
1
  • Ortholog Compara
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
GO biological process 
Dendrite morphogenesisdefinition[GO:0048813]  
1
  • UniProtKB
Lysosome localizationdefinition[GO:0032418]  
1
  • UniProtKB
Microtubule cytoskeleton organizationdefinition[GO:0000226] silver  
1
  • InterPro 2 GO
Transportdefinition[GO:0006810]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MAP6
GenomeRNAi: 4135
PRO: PR:Q96JE9