RNF170 - E3 ubiquitin-protein ligase RNF170 - human protein (Function)
 
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Protein
Gene
References

 
RNF170 »  E3 ubiquitin-protein ligase RNF170
 
Gene name:  RNF170
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.  
1
  • CuratedUniProtKB
GO molecular function 
Ligase activitydefinition[GO:0016874]  
  • IEAUniProtKB KW
Zinc ion bindingdefinition[GO:0008270] silver  
  • IEAInterPro 2 GO
GO biological process 
Protein ubiquitinationdefinition[GO:0016567]  
  • IEAUniPathway
Pathways 
This protein is involved in the following pathway
 

Keywords

Biological process 
Ubl conjugation pathway  definition   [KW-0833]
Molecular function 
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 81790
PRO: PR:Q96K19