NEUROD6 - Neurogenic differentiation factor 6 - human protein (Function)
 
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Protein
Gene
References

 
NEUROD6 »  Neurogenic differentiation factor 6  (NeuroD6)
 
Protein also known as:  Class A basic helix-loop-helix protein 2 (bHLHa2).
Gene name:  NEUROD6
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity).  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
Protein dimerization activitydefinition[GO:0046983] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Dentate gyrus developmentdefinition[GO:0021542] silver  
  • IEAOrtholog Compara
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
  • IEAUniProtKB KW
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 63974
PRO: PR:Q96NK8