KCNC2 - Potassium voltage-gated channel subfamily C member 2 - human protein (Function)
 
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KCNC2 »  Potassium voltage-gated channel subfamily C member 2
 
Protein also known as:  Voltage-gated potassium channel Kv3.2.
Gene name:  KCNC2
Entry whose protein(s) existence is based on evidence at protein level
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1 38 6
GENE REF ISO

Function

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Overview 
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly (By similarity).  
1
  • UniProtKB
GO molecular function 
Delayed rectifier potassium channel activitydefinition[GO:0005251]  
2
  • Ortholog Curator
  • RefGenome
Voltage-gated potassium channel activitydefinition[GO:0005249]  
1
  • Ortholog Curator
GO biological process 
Action potentialdefinition[GO:0001508] silver  
1
  • Ortholog Compara
Cellular response to nitric oxidedefinition[GO:0071732]  
1
  • Ortholog Curator
Nitric oxide-cGMP-mediated signaling pathwaydefinition[GO:0038060]  
1
  • Ortholog Curator
Potassium ion transmembrane transportdefinition[GO:0071805]  
2
  • Ortholog Curator
  • RefGenome
Protein heterooligomerizationdefinition[GO:0051291]  
1
  • Ortholog Curator
Protein homooligomerizationdefinition[GO:0051260]  
1
  • Ortholog Curator
Regulation of ion transmembrane transportdefinition[GO:0034765]  
1
  • UniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion  REACT_18274  
Voltage gated Potassium channels  REACT_75770  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNC2
GenomeRNAi: 3747
PRO: PR:Q96PR1
Chemistry
GuidetoPHARMACOLOGY: 549