VPS35 - Vacuolar protein sorting-associated protein 35 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
VPS35 »  Vacuolar protein sorting-associated protein 35
 
Protein also known as:  Vesicle protein sorting 35.
Gene name:  VPS35
Family name: VPS35
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 52 1
GENE REF ISO

Function

 show evidences
Overview 
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).  
1
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
GO biological process 
Cell deathdefinition[GO:0008219]  
  • IEAUniProtKB KW
Protein transportdefinition[GO:0015031]  
  • IEAUniProtKB KW
Retrograde transport, endosome to Golgidefinition[GO:0042147]  
1
  • NASUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: VPS35
GenomeRNAi: 55737
PRO: PR:Q96QK1