ARX - Homeobox protein ARX - human protein (Function)
 
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Protein
Gene
References

 
ARX »  Homeobox protein ARX
 
Protein also known as:  Aristaless-related homeobox.
Gene name:  ARX
Family name: Paired homeobox » Bicoid
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.  
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Axon guidancedefinition[GO:0007411] silver  
  • IEAOrtholog Compara
Cell proliferation in forebraindefinition[GO:0021846] silver  
  • IEAOrtholog Compara
Cerebral cortex GABAergic interneuron migrationdefinition[GO:0021853] silver  
  • IEAOrtholog Compara
Cerebral cortex tangential migrationdefinition[GO:0021800] silver  
  • IEAOrtholog Compara
Embryonic olfactory bulb interneuron precursor migrationdefinition[GO:0021831] silver  
  • IEAOrtholog Compara
Epithelial cell fate commitmentdefinition[GO:0072148] silver  
  • IEAOrtholog Compara
Globus pallidus developmentdefinition[GO:0021759] silver  
  • IEAOrtholog Compara
Lipid digestiondefinition[GO:0044241] silver  
  • IEAOrtholog Compara
Neuron migrationdefinition[GO:0001764] silver  
  • IEAOrtholog Compara
Positive regulation of organ growthdefinition[GO:0046622] silver  
  • IEAOrtholog Compara
Regulation of cell proliferationdefinition[GO:0042127] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links