ARX - Homeobox protein ARX - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
ARX »  Homeobox protein ARX
 
Protein also known as:  Aristaless-related homeobox.
Gene name:  ARX
Family name: Paired homeobox » Bicoid
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 54 1
GENE REF ISO

Function

 show evidences
Overview 
Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.  
1
  • UniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
1
  • Ortholog Compara
RNA polymerase II distal enhancer sequence-specific DNA bindingdefinition[GO:0000980] silver  
1
  • Ortholog Compara
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptiondefinition[GO:0001206] silver  
1
  • Ortholog Compara
GO biological process 
Axon guidancedefinition[GO:0007411] silver  
1
  • Ortholog Compara
Cell proliferation in forebraindefinition[GO:0021846] silver  
1
  • Ortholog Compara
Cerebral cortex GABAergic interneuron migrationdefinition[GO:0021853] silver  
1
  • Ortholog Compara
Cerebral cortex tangential migrationdefinition[GO:0021800] silver  
1
  • Ortholog Compara
Embryonic olfactory bulb interneuron precursor migrationdefinition[GO:0021831] silver  
1
  • Ortholog Compara
Epithelial cell fate commitmentdefinition[GO:0072148] silver  
1
  • Ortholog Compara
Globus pallidus developmentdefinition[GO:0021759] silver  
1
  • Ortholog Compara
Lipid digestiondefinition[GO:0044241] silver  
1
  • Ortholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
1
  • Ortholog Compara
Positive regulation of organ growthdefinition[GO:0046622] silver  
1
  • Ortholog Compara
Regulation of cell proliferationdefinition[GO:0042127] silver  
1
  • Ortholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links