IL4I1 - L-amino-acid oxidase - human protein (Function)
 
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Protein
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IL4I1 »  L-amino-acid oxidase   [ EC 1.4.3.2 ]  (LAO)
 
Protein also known as:  Interleukin-4-induced protein 1 (IL4-induced protein 1).
Gene name:  IL4I1
Family name: Flavin monoamine oxidase » FIG1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).  
  • CuratedUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 1.4.3.2: An L-amino acid + H(2)O + O(2) a 2-oxo acid + NH(3) + H(2)O(2).  
  • CuratedUniProtKB
It requires the following cofactor
FAD (By similarity).  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Alanine, aspartate and glutamate metabolism  hsa00250+259307  
Cysteine and methionine metabolism  hsa00270+259307  
Metabolic pathways  hsa01100+259307  
Phenylalanine metabolism  hsa00360+259307  
Phenylalanine, tyrosine and tryptophan biosynthesis  hsa00400+259307  
Tryptophan metabolism  hsa00380+259307  
Tyrosine metabolism  hsa00350+259307  
Valine, leucine and isoleucine degradation  hsa00280+259307  
According to Reactome, this protein belongs to the following pathway:
Disease  REACT_116125  
 

Keywords

Molecular function 
Oxidoreductase  definition   [KW-0560]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 259307
PRO: PR:Q96RQ9