IFT140 - Intraflagellar transport protein 140 homolog - human protein (Function)
 
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Protein
Gene
References

 
IFT140 »  Intraflagellar transport protein 140 homolog
 
Protein also known as:  WD and tetratricopeptide repeats protein 2.
Gene name:  IFT140
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 35 2
GENE REF ISO

Function

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Overview 
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance.  
2
  • UniProtKB
GO biological process 
Cilium assemblydefinition[GO:0042384] silver  
1
  • Ortholog Compara
Intraciliary retrograde transportdefinition[GO:0035721]  
1
  • RefGenome
Protein localization to ciliumdefinition[GO:0061512]  
2
  • UniProtKB
  • MGI
Regulation of cilium assemblydefinition[GO:1902017]  
1
  • UniProtKB
Renal system developmentdefinition[GO:0072001]  
2
  • UniProtKB
Retina development in camera-type eyedefinition[GO:0060041]  
2
  • UniProtKB
Skeletal system morphogenesisdefinition[GO:0048705]  
2
  • UniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
Hedgehog 'off' state  REACT_268323  
Intraflagellar transport  REACT_268024  
 

Keywords

Biological process 
Cilium biogenesis/degradation  definition   [KW-0970]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 9742
PRO: PR:Q96RY7