RBM15 - Putative RNA-binding protein 15 - human protein (Function)
 
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RBM15 »  Putative RNA-binding protein 15
 
Protein also known as:  RNA-binding motif protein 15.
Gene name:  RBM15
Family name: RRM Spen
Entry whose protein(s) existence is based on evidence at protein level
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1 48 4
GENE REF ISO

Function

 show evidences
Overview 
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.  
2
  • CuratedUniProtKB
GO molecular function 
Nucleotide bindingdefinition[GO:0000166] silver  
  • IEAInterPro 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
GO biological process 
Negative regulation of myeloid cell differentiationdefinition[GO:0045638] silver  
  • IEAOrtholog Compara
Not  Negative regulation of transcription, DNA-templateddefinition[GO:0045892]  
1
  • IDAUniProtKB
Patterning of blood vesselsdefinition[GO:0001569] silver  
  • IEAOrtholog Compara
Placenta blood vessel developmentdefinition[GO:0060674] silver  
  • IEAOrtholog Compara
Positive regulation of transcription of Notch receptor targetdefinition[GO:0007221] silver  
  • IEAOrtholog Compara
Spleen developmentdefinition[GO:0048536] silver  
  • IEAOrtholog Compara
Ventricular septum morphogenesisdefinition[GO:0060412] silver  
  • IEAOrtholog Compara
Viral processdefinition[GO:0016032]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RBM15
GenomeRNAi: 64783
PRO: PR:Q96T37